diff --git a/hw/display/vhost-user-gpu.c b/hw/display/vhost-user-gpu.c
index 19c0e20103..4380a5e672 100644
--- a/hw/display/vhost-user-gpu.c
+++ b/hw/display/vhost-user-gpu.c
@@ -486,6 +486,15 @@ vhost_user_gpu_guest_notifier_pending(VirtIODevice *vdev, int idx)
 {
     VhostUserGPU *g = VHOST_USER_GPU(vdev);
 
+    /*
+     * Add the check for configure interrupt, Use VIRTIO_CONFIG_IRQ_IDX -1
+     * as the Marco of configure interrupt's IDX, If this driver does not
+     * support, the function will return
+     */
+
+    if (idx == VIRTIO_CONFIG_IRQ_IDX) {
+        return false;
+    }
     return vhost_virtqueue_pending(&g->vhost->dev, idx);
 }
 
@@ -494,6 +503,15 @@ vhost_user_gpu_guest_notifier_mask(VirtIODevice *vdev, int idx, bool mask)
 {
     VhostUserGPU *g = VHOST_USER_GPU(vdev);
 
+    /*
+     * Add the check for configure interrupt, Use VIRTIO_CONFIG_IRQ_IDX -1
+     * as the Marco of configure interrupt's IDX, If this driver does not
+     * support, the function will return
+     */
+
+    if (idx == VIRTIO_CONFIG_IRQ_IDX) {
+        return;
+    }
     vhost_virtqueue_mask(&g->vhost->dev, vdev, idx, mask);
 }
 
diff --git a/hw/net/virtio-net.c b/hw/net/virtio-net.c
index e9f696b4cf..0cc4ee7c7c 100644
--- a/hw/net/virtio-net.c
+++ b/hw/net/virtio-net.c
@@ -3216,6 +3216,15 @@ static bool virtio_net_guest_notifier_pending(VirtIODevice *vdev, int idx)
     } else {
         nc = qemu_get_subqueue(n->nic, vq2q(idx));
     }
+    /*
+     * Add the check for configure interrupt, Use VIRTIO_CONFIG_IRQ_IDX -1
+     * as the Marco of configure interrupt's IDX, If this driver does not
+     * support, the function will return false
+     */
+
+    if (idx == VIRTIO_CONFIG_IRQ_IDX) {
+        return false;
+    }
     return vhost_net_virtqueue_pending(get_vhost_net(nc->peer), idx);
 }
 
@@ -3239,8 +3248,17 @@ static void virtio_net_guest_notifier_mask(VirtIODevice *vdev, int idx,
     } else {
         nc = qemu_get_subqueue(n->nic, vq2q(idx));
     }
-    vhost_net_virtqueue_mask(get_vhost_net(nc->peer),
-                             vdev, idx, mask);
+    /*
+     *Add the check for configure interrupt, Use VIRTIO_CONFIG_IRQ_IDX -1
+     * as the Marco of configure interrupt's IDX, If this driver does not
+     * support, the function will return
+     */
+
+    if (idx == VIRTIO_CONFIG_IRQ_IDX) {
+        return;
+    }
+
+    vhost_net_virtqueue_mask(get_vhost_net(nc->peer), vdev, idx, mask);
 }
 
 static void virtio_net_set_config_size(VirtIONet *n, uint64_t host_features)
diff --git a/hw/virtio/vhost-user-fs.c b/hw/virtio/vhost-user-fs.c
index ad0f91c607..1a5a10a21d 100644
--- a/hw/virtio/vhost-user-fs.c
+++ b/hw/virtio/vhost-user-fs.c
@@ -158,6 +158,15 @@ static void vuf_guest_notifier_mask(VirtIODevice *vdev, int idx,
 {
     VHostUserFS *fs = VHOST_USER_FS(vdev);
 
+    /*
+     * Add the check for configure interrupt, Use VIRTIO_CONFIG_IRQ_IDX -1
+     * as the Marco of configure interrupt's IDX, If this driver does not
+     * support, the function will return
+     */
+
+    if (idx == VIRTIO_CONFIG_IRQ_IDX) {
+        return;
+    }
     vhost_virtqueue_mask(&fs->vhost_dev, vdev, idx, mask);
 }
 
@@ -165,6 +174,15 @@ static bool vuf_guest_notifier_pending(VirtIODevice *vdev, int idx)
 {
     VHostUserFS *fs = VHOST_USER_FS(vdev);
 
+    /*
+     * Add the check for configure interrupt, Use VIRTIO_CONFIG_IRQ_IDX -1
+     * as the Marco of configure interrupt's IDX, If this driver does not
+     * support, the function will return
+     */
+
+    if (idx == VIRTIO_CONFIG_IRQ_IDX) {
+        return false;
+    }
     return vhost_virtqueue_pending(&fs->vhost_dev, idx);
 }
 
diff --git a/hw/virtio/vhost-user-gpio.c b/hw/virtio/vhost-user-gpio.c
index 8b40fe450c..93a405ab99 100644
--- a/hw/virtio/vhost-user-gpio.c
+++ b/hw/virtio/vhost-user-gpio.c
@@ -193,6 +193,16 @@ static void vu_gpio_guest_notifier_mask(VirtIODevice *vdev, int idx, bool mask)
 {
     VHostUserGPIO *gpio = VHOST_USER_GPIO(vdev);
 
+    /*
+     * Add the check for configure interrupt, Use VIRTIO_CONFIG_IRQ_IDX -1
+     * as the Marco of configure interrupt's IDX, If this driver does not
+     * support, the function will return
+     */
+
+    if (idx == VIRTIO_CONFIG_IRQ_IDX) {
+        return;
+    }
+
     vhost_virtqueue_mask(&gpio->vhost_dev, vdev, idx, mask);
 }
 
diff --git a/hw/virtio/vhost-vsock-common.c b/hw/virtio/vhost-vsock-common.c
index 29b9ab4f72..ce3597a7ab 100644
--- a/hw/virtio/vhost-vsock-common.c
+++ b/hw/virtio/vhost-vsock-common.c
@@ -126,6 +126,15 @@ static void vhost_vsock_common_guest_notifier_mask(VirtIODevice *vdev, int idx,
 {
     VHostVSockCommon *vvc = VHOST_VSOCK_COMMON(vdev);
 
+    /*
+     * Add the check for configure interrupt, Use VIRTIO_CONFIG_IRQ_IDX -1
+     * as the Marco of configure interrupt's IDX, If this driver does not
+     * support, the function will return
+     */
+
+    if (idx == VIRTIO_CONFIG_IRQ_IDX) {
+        return;
+    }
     vhost_virtqueue_mask(&vvc->vhost_dev, vdev, idx, mask);
 }
 
@@ -134,6 +143,15 @@ static bool vhost_vsock_common_guest_notifier_pending(VirtIODevice *vdev,
 {
     VHostVSockCommon *vvc = VHOST_VSOCK_COMMON(vdev);
 
+    /*
+     * Add the check for configure interrupt, Use VIRTIO_CONFIG_IRQ_IDX -1
+     * as the Marco of configure interrupt's IDX, If this driver does not
+     * support, the function will return
+     */
+
+    if (idx == VIRTIO_CONFIG_IRQ_IDX) {
+        return false;
+    }
     return vhost_virtqueue_pending(&vvc->vhost_dev, idx);
 }
 
diff --git a/hw/virtio/virtio-crypto.c b/hw/virtio/virtio-crypto.c
index df4bde210b..277f657339 100644
--- a/hw/virtio/virtio-crypto.c
+++ b/hw/virtio/virtio-crypto.c
@@ -1139,6 +1139,15 @@ static void virtio_crypto_guest_notifier_mask(VirtIODevice *vdev, int idx,
 
     assert(vcrypto->vhost_started);
 
+    /*
+     * Add the check for configure interrupt, Use VIRTIO_CONFIG_IRQ_IDX -1
+     * as the Marco of configure interrupt's IDX, If this driver does not
+     * support, the function will return
+     */
+
+    if (idx == VIRTIO_CONFIG_IRQ_IDX) {
+        return;
+    }
     cryptodev_vhost_virtqueue_mask(vdev, queue, idx, mask);
 }
 
@@ -1149,6 +1158,15 @@ static bool virtio_crypto_guest_notifier_pending(VirtIODevice *vdev, int idx)
 
     assert(vcrypto->vhost_started);
 
+    /*
+     * Add the check for configure interrupt, Use VIRTIO_CONFIG_IRQ_IDX -1
+     * as the Marco of configure interrupt's IDX, If this driver does not
+     * support, the function will return
+     */
+
+    if (idx == VIRTIO_CONFIG_IRQ_IDX) {
+        return false;
+    }
     return cryptodev_vhost_virtqueue_pending(vdev, queue, idx);
 }
 
diff --git a/include/hw/virtio/virtio.h b/include/hw/virtio/virtio.h
index f41b4a7e64..a9953cf8b0 100644
--- a/include/hw/virtio/virtio.h
+++ b/include/hw/virtio/virtio.h
@@ -79,6 +79,9 @@ typedef struct VirtQueueElement
 
 #define VIRTIO_NO_VECTOR 0xffff
 
+/* special index value used internally for config irqs */
+#define VIRTIO_CONFIG_IRQ_IDX -1
+
 #define TYPE_VIRTIO_DEVICE "virtio-device"
 OBJECT_DECLARE_TYPE(VirtIODevice, VirtioDeviceClass, VIRTIO_DEVICE)
 
