diff --git a/include/exec/cpu-defs.h b/include/exec/cpu-defs.h
index a6e0cf1812..b757d37966 100644
--- a/include/exec/cpu-defs.h
+++ b/include/exec/cpu-defs.h
@@ -65,11 +65,7 @@
 /* use a fully associative victim tlb of 8 entries */
 #define CPU_VTLB_SIZE 8
 
-#if HOST_LONG_BITS == 32 && TARGET_LONG_BITS == 32
-#define CPU_TLB_ENTRY_BITS 4
-#else
 #define CPU_TLB_ENTRY_BITS 5
-#endif
 
 #define CPU_TLB_DYN_MIN_BITS 6
 #define CPU_TLB_DYN_DEFAULT_BITS 8
@@ -95,33 +91,26 @@
 # endif
 
 /* Minimalized TLB entry for use by TCG fast path. */
-typedef struct CPUTLBEntry {
-    /* bit TARGET_LONG_BITS to TARGET_PAGE_BITS : virtual address
-       bit TARGET_PAGE_BITS-1..4  : Nonzero for accesses that should not
-                                    go directly to ram.
-       bit 3                      : indicates that the entry is invalid
-       bit 2..0                   : zero
-    */
-    union {
-        struct {
-            target_ulong addr_read;
-            target_ulong addr_write;
-            target_ulong addr_code;
-            /* Addend to virtual address to get host address.  IO accesses
-               use the corresponding iotlb value.  */
-            uintptr_t addend;
-        };
+typedef union CPUTLBEntry {
+    struct {
+        uint64_t addr_read;
+        uint64_t addr_write;
+        uint64_t addr_code;
         /*
-         * Padding to get a power of two size, as well as index
-         * access to addr_{read,write,code}.
+         * Addend to virtual address to get host address.  IO accesses
+         * use the corresponding iotlb value.
          */
-        target_ulong addr_idx[(1 << CPU_TLB_ENTRY_BITS) / TARGET_LONG_SIZE];
+        uintptr_t addend;
     };
+    /*
+     * Padding to get a power of two size, as well as index
+     * access to addr_{read,write,code}.
+     */
+    uint64_t addr_idx[(1 << CPU_TLB_ENTRY_BITS) / sizeof(uint64_t)];
 } CPUTLBEntry;
 
 QEMU_BUILD_BUG_ON(sizeof(CPUTLBEntry) != (1 << CPU_TLB_ENTRY_BITS));
 
-
 #endif  /* !CONFIG_USER_ONLY && CONFIG_TCG */
 
 #if !defined(CONFIG_USER_ONLY)
diff --git a/include/exec/cpu_ldst.h b/include/exec/cpu_ldst.h
index 5939688f69..a43b34e46b 100644
--- a/include/exec/cpu_ldst.h
+++ b/include/exec/cpu_ldst.h
@@ -334,18 +334,25 @@ static inline target_ulong tlb_read_idx(const CPUTLBEntry *entry,
 {
     /* Do not rearrange the CPUTLBEntry structure members. */
     QEMU_BUILD_BUG_ON(offsetof(CPUTLBEntry, addr_read) !=
-                      MMU_DATA_LOAD * TARGET_LONG_SIZE);
+                      MMU_DATA_LOAD * sizeof(uint64_t));
     QEMU_BUILD_BUG_ON(offsetof(CPUTLBEntry, addr_write) !=
-                      MMU_DATA_STORE * TARGET_LONG_SIZE);
+                      MMU_DATA_STORE * sizeof(uint64_t));
     QEMU_BUILD_BUG_ON(offsetof(CPUTLBEntry, addr_code) !=
-                      MMU_INST_FETCH * TARGET_LONG_SIZE);
+                      MMU_INST_FETCH * sizeof(uint64_t));
 
-    const target_ulong *ptr = &entry->addr_idx[access_type];
-#if TCG_OVERSIZED_GUEST
-    return *ptr;
+#if TARGET_LONG_BITS == 32
+    /* Use qatomic_read, in case of addr_write; only care about low bits. */
+    const uint32_t *ptr = (uint32_t *)&entry->addr_idx[access_type];
+    ptr += HOST_BIG_ENDIAN;
+    return qatomic_read(ptr);
 #else
+    const uint64_t *ptr = &entry->addr_idx[access_type];
+# if TCG_OVERSIZED_GUEST
+    return *ptr;
+# else
     /* ofs might correspond to .addr_write, so use qatomic_read */
     return qatomic_read(ptr);
+# endif
 #endif
 }
 
diff --git a/accel/tcg/cputlb.c b/accel/tcg/cputlb.c
index 90c72c9940..6beaeb0a81 100644
--- a/accel/tcg/cputlb.c
+++ b/accel/tcg/cputlb.c
@@ -1000,11 +1000,15 @@ static void tlb_reset_dirty_range_locked(CPUTLBEntry *tlb_entry,
         addr &= TARGET_PAGE_MASK;
         addr += tlb_entry->addend;
         if ((addr - start) < length) {
-#if TCG_OVERSIZED_GUEST
+#if TARGET_LONG_BITS == 32
+            uint32_t *ptr_write = (uint32_t *)&tlb_entry->addr_write;
+            ptr_write += HOST_BIG_ENDIAN;
+            qatomic_set(ptr_write, *ptr_write | TLB_NOTDIRTY);
+#elif TCG_OVERSIZED_GUEST
             tlb_entry->addr_write |= TLB_NOTDIRTY;
 #else
             qatomic_set(&tlb_entry->addr_write,
-                       tlb_entry->addr_write | TLB_NOTDIRTY);
+                        tlb_entry->addr_write | TLB_NOTDIRTY);
 #endif
         }
     }
diff --git a/tcg/aarch64/tcg-target.c.inc b/tcg/aarch64/tcg-target.c.inc
index 261ad25210..e23c57e2cd 100644
--- a/tcg/aarch64/tcg-target.c.inc
+++ b/tcg/aarch64/tcg-target.c.inc
@@ -1690,6 +1690,7 @@ static TCGLabelQemuLdst *prepare_host_addr(TCGContext *s, HostAddress *h,
     tcg_out_insn(s, 3502, ADD, 1, TCG_REG_TMP1, TCG_REG_TMP1, TCG_REG_TMP0);
 
     /* Load the tlb comparator into TMP0, and the fast path addend into TMP1. */
+    QEMU_BUILD_BUG_ON(HOST_BIG_ENDIAN);
     tcg_out_ld(s, addr_type, TCG_REG_TMP0, TCG_REG_TMP1,
                is_ld ? offsetof(CPUTLBEntry, addr_read)
                      : offsetof(CPUTLBEntry, addr_write));
diff --git a/tcg/arm/tcg-target.c.inc b/tcg/arm/tcg-target.c.inc
index 20cc1cc477..64eb0cb5dc 100644
--- a/tcg/arm/tcg-target.c.inc
+++ b/tcg/arm/tcg-target.c.inc
@@ -1430,6 +1430,7 @@ static TCGLabelQemuLdst *prepare_host_addr(TCGContext *s, HostAddress *h,
      * Add the tlb_table pointer, creating the CPUTLBEntry address in R1.
      * Load the tlb comparator into R2/R3 and the fast path addend into R1.
      */
+    QEMU_BUILD_BUG_ON(HOST_BIG_ENDIAN);
     if (cmp_off == 0) {
         if (s->addr_type == TCG_TYPE_I32) {
             tcg_out_ld32_rwb(s, COND_AL, TCG_REG_R2, TCG_REG_R1, TCG_REG_R0);
diff --git a/tcg/loongarch64/tcg-target.c.inc b/tcg/loongarch64/tcg-target.c.inc
index 0bae922982..e89f3b848b 100644
--- a/tcg/loongarch64/tcg-target.c.inc
+++ b/tcg/loongarch64/tcg-target.c.inc
@@ -875,6 +875,7 @@ static TCGLabelQemuLdst *prepare_host_addr(TCGContext *s, HostAddress *h,
     tcg_out_opc_add_d(s, TCG_REG_TMP2, TCG_REG_TMP2, TCG_REG_TMP1);
 
     /* Load the tlb comparator and the addend.  */
+    QEMU_BUILD_BUG_ON(HOST_BIG_ENDIAN);
     tcg_out_ld(s, addr_type, TCG_REG_TMP0, TCG_REG_TMP2,
                is_ld ? offsetof(CPUTLBEntry, addr_read)
                      : offsetof(CPUTLBEntry, addr_write));
diff --git a/tcg/mips/tcg-target.c.inc b/tcg/mips/tcg-target.c.inc
index 3274d9aace..4c0de0a380 100644
--- a/tcg/mips/tcg-target.c.inc
+++ b/tcg/mips/tcg-target.c.inc
@@ -1311,14 +1311,17 @@ static TCGLabelQemuLdst *prepare_host_addr(TCGContext *s, HostAddress *h,
     /* Add the tlb_table pointer, creating the CPUTLBEntry address in TMP3.  */
     tcg_out_opc_reg(s, ALIAS_PADD, TCG_TMP3, TCG_TMP3, TCG_TMP1);
 
+    if (TCG_TARGET_REG_BITS == 32 || addr_type == TCG_TYPE_I32) {
+        /* Load the (low half) tlb comparator.  */
+        tcg_out_ld(s, TCG_TYPE_I32, TCG_TMP0, TCG_TMP3,
+                   cmp_off + HOST_BIG_ENDIAN * 4);
+    } else {
+        tcg_out_ld(s, TCG_TYPE_I64, TCG_TMP0, TCG_TMP3, cmp_off);
+    }
+
     if (TCG_TARGET_REG_BITS == 64 || addr_type == TCG_TYPE_I32) {
-        /* Load the tlb comparator.  */
-        tcg_out_ld(s, addr_type, TCG_TMP0, TCG_TMP3, cmp_off);
         /* Load the tlb addend for the fast path.  */
         tcg_out_ld(s, TCG_TYPE_PTR, TCG_TMP3, TCG_TMP3, add_off);
-    } else {
-        /* Load the low half of the tlb comparator.  */
-        tcg_out_ldst(s, OPC_LW, TCG_TMP0, TCG_TMP3, cmp_off + LO_OFF);
     }
 
     /*
diff --git a/tcg/ppc/tcg-target.c.inc b/tcg/ppc/tcg-target.c.inc
index 11955a6cc2..73f6ea0393 100644
--- a/tcg/ppc/tcg-target.c.inc
+++ b/tcg/ppc/tcg-target.c.inc
@@ -2098,20 +2098,24 @@ static TCGLabelQemuLdst *prepare_host_addr(TCGContext *s, HostAddress *h,
     }
     tcg_out32(s, AND | SAB(TCG_REG_TMP1, TCG_REG_TMP1, TCG_REG_R0));
 
-    /* Load the (low part) TLB comparator into TMP2.  */
-    if (cmp_off == 0
-        && (TCG_TARGET_REG_BITS == 64 || addr_type == TCG_TYPE_I32)) {
-        uint32_t lxu = (TCG_TARGET_REG_BITS == 32 || addr_type == TCG_TYPE_I32
-                        ? LWZUX : LDUX);
-        tcg_out32(s, lxu | TAB(TCG_REG_TMP2, TCG_REG_TMP1, TCG_REG_TMP2));
+    /*
+     * Load the (low part) TLB comparator into TMP2.
+     * For 64-bit host, always load the entire 64-bit slot for simplicity.
+     * We will ignore the high bits with tcg_out_cmp(..., addr_type).
+     */
+    if (TCG_TARGET_REG_BITS == 64) {
+        if (cmp_off == 0) {
+            tcg_out32(s, LDUX | TAB(TCG_REG_TMP2, TCG_REG_TMP1, TCG_REG_TMP2));
+        } else {
+            tcg_out32(s, ADD | TAB(TCG_REG_TMP1, TCG_REG_TMP1, TCG_REG_TMP2));
+            tcg_out_ld(s, TCG_TYPE_I64, TCG_REG_TMP2, TCG_REG_TMP1, cmp_off);
+        }
+    } else if (cmp_off == 0 && !HOST_BIG_ENDIAN) {
+        tcg_out32(s, LWZUX | TAB(TCG_REG_TMP2, TCG_REG_TMP1, TCG_REG_TMP2));
     } else {
         tcg_out32(s, ADD | TAB(TCG_REG_TMP1, TCG_REG_TMP1, TCG_REG_TMP2));
-        if (TCG_TARGET_REG_BITS == 32 && addr_type != TCG_TYPE_I32) {
-            tcg_out_ld(s, TCG_TYPE_I32, TCG_REG_TMP2,
-                       TCG_REG_TMP1, cmp_off + 4 * HOST_BIG_ENDIAN);
-        } else {
-            tcg_out_ld(s, addr_type, TCG_REG_TMP2, TCG_REG_TMP1, cmp_off);
-        }
+        tcg_out_ld(s, TCG_TYPE_I32, TCG_REG_TMP2, TCG_REG_TMP1,
+                   cmp_off + 4 * HOST_BIG_ENDIAN);
     }
 
     /*
diff --git a/tcg/riscv/tcg-target.c.inc b/tcg/riscv/tcg-target.c.inc
index a8f99f7e77..a6d56e2d0e 100644
--- a/tcg/riscv/tcg-target.c.inc
+++ b/tcg/riscv/tcg-target.c.inc
@@ -1249,6 +1249,7 @@ static TCGLabelQemuLdst *prepare_host_addr(TCGContext *s, TCGReg *pbase,
     }
 
     /* Load the tlb comparator and the addend.  */
+    QEMU_BUILD_BUG_ON(HOST_BIG_ENDIAN);
     tcg_out_ld(s, addr_type, TCG_REG_TMP0, TCG_REG_TMP2,
                is_ld ? offsetof(CPUTLBEntry, addr_read)
                      : offsetof(CPUTLBEntry, addr_write));
diff --git a/tcg/s390x/tcg-target.c.inc b/tcg/s390x/tcg-target.c.inc
index 2795242b60..03be800c3b 100644
--- a/tcg/s390x/tcg-target.c.inc
+++ b/tcg/s390x/tcg-target.c.inc
@@ -1796,6 +1796,7 @@ static TCGLabelQemuLdst *prepare_host_addr(TCGContext *s, HostAddress *h,
         ofs = offsetof(CPUTLBEntry, addr_write);
     }
     if (addr_type == TCG_TYPE_I32) {
+        ofs += HOST_BIG_ENDIAN * 4;
         tcg_out_insn(s, RX, C, TCG_REG_R0, TCG_TMP0, TCG_REG_NONE, ofs);
     } else {
         tcg_out_insn(s, RXY, CG, TCG_REG_R0, TCG_TMP0, TCG_REG_NONE, ofs);
diff --git a/tcg/sparc64/tcg-target.c.inc b/tcg/sparc64/tcg-target.c.inc
index 48efd83817..6c60657c36 100644
--- a/tcg/sparc64/tcg-target.c.inc
+++ b/tcg/sparc64/tcg-target.c.inc
@@ -1063,8 +1063,12 @@ static TCGLabelQemuLdst *prepare_host_addr(TCGContext *s, HostAddress *h,
     /* Add the tlb_table pointer, creating the CPUTLBEntry address into R2.  */
     tcg_out_arith(s, TCG_REG_T1, TCG_REG_T1, TCG_REG_T3, ARITH_ADD);
 
-    /* Load the tlb comparator and the addend. */
-    tcg_out_ld(s, addr_type, TCG_REG_T2, TCG_REG_T1, cmp_off);
+    /*
+     * Load the tlb comparator and the addend.
+     * Always load the entire 64-bit comparator for simplicity.
+     * We will ignore the high bits via BPCC_ICC below.
+     */
+    tcg_out_ld(s, TCG_TYPE_I64, TCG_REG_T2, TCG_REG_T1, cmp_off);
     tcg_out_ld(s, TCG_TYPE_PTR, TCG_REG_T1, TCG_REG_T1, add_off);
     h->base = TCG_REG_T1;
 
