diff --git a/hw/virtio/vhost.c b/hw/virtio/vhost.c
index 24013b39d6..503a160c96 100644
--- a/hw/virtio/vhost.c
+++ b/hw/virtio/vhost.c
@@ -707,7 +707,7 @@ static void vhost_region_add_section(struct vhost_dev *dev,
                                                mrs_size, mrs_host);
     }
 
-    if (dev->n_tmp_sections) {
+    if (dev->n_tmp_sections && !section->unmergeable) {
         /* Since we already have at least one section, lets see if
          * this extends it; since we're scanning in order, we only
          * have to look at the last one, and the FlatView that calls
@@ -740,7 +740,7 @@ static void vhost_region_add_section(struct vhost_dev *dev,
             size_t offset = mrs_gpa - prev_gpa_start;
 
             if (prev_host_start + offset == mrs_host &&
-                section->mr == prev_sec->mr) {
+                section->mr == prev_sec->mr && !prev_sec->unmergeable) {
                 uint64_t max_end = MAX(prev_host_end, mrs_host + mrs_size);
                 need_add = false;
                 prev_sec->offset_within_address_space =
diff --git a/include/exec/memory.h b/include/exec/memory.h
index 73062edf49..38b22b4fe0 100644
--- a/include/exec/memory.h
+++ b/include/exec/memory.h
@@ -95,6 +95,7 @@ struct ReservedRegion {
  *     relative to the region's address space
  * @readonly: writes to this section are ignored
  * @nonvolatile: this section is non-volatile
+ * @unmergeable: this section should not get merged with adjacent sections
  */
 struct MemoryRegionSection {
     Int128 size;
@@ -104,6 +105,7 @@ struct MemoryRegionSection {
     hwaddr offset_within_address_space;
     bool readonly;
     bool nonvolatile;
+    bool unmergeable;
 };
 
 typedef struct IOMMUTLBEntry IOMMUTLBEntry;
@@ -773,6 +775,7 @@ struct MemoryRegion {
     bool nonvolatile;
     bool rom_device;
     bool flush_coalesced_mmio;
+    bool unmergeable;
     uint8_t dirty_log_mask;
     bool is_iommu;
     RAMBlock *ram_block;
@@ -2351,6 +2354,25 @@ void memory_region_set_size(MemoryRegion *mr, uint64_t size);
 void memory_region_set_alias_offset(MemoryRegion *mr,
                                     hwaddr offset);
 
+/*
+ * memory_region_set_unmergeable: Set a memory region unmergeable
+ *
+ * Mark a memory region unmergeable, resulting in the memory region (or
+ * everything contained in a memory region container) not getting merged when
+ * simplifying the address space and notifying memory listeners. Consequently,
+ * memory listeners will never get notified about ranges that are larger than
+ * the original memory regions.
+ *
+ * This is primarily useful when multiple aliases to a RAM memory region are
+ * mapped into a memory region container, and updates (e.g., enable/disable or
+ * map/unmap) of individual memory region aliases are not supposed to affect
+ * other memory regions in the same container.
+ *
+ * @mr: the #MemoryRegion to be updated
+ * @unmergeable: whether to mark the #MemoryRegion unmergeable
+ */
+void memory_region_set_unmergeable(MemoryRegion *mr, bool unmergeable);
+
 /**
  * memory_region_present: checks if an address relative to a @container
  * translates into #MemoryRegion within @container
diff --git a/softmmu/memory.c b/softmmu/memory.c
index 9d491d488b..8125eac927 100644
--- a/softmmu/memory.c
+++ b/softmmu/memory.c
@@ -224,6 +224,7 @@ struct FlatRange {
     bool romd_mode;
     bool readonly;
     bool nonvolatile;
+    bool unmergeable;
 };
 
 #define FOR_EACH_FLAT_RANGE(var, view)          \
@@ -240,6 +241,7 @@ section_from_flat_range(FlatRange *fr, FlatView *fv)
         .offset_within_address_space = int128_get64(fr->addr.start),
         .readonly = fr->readonly,
         .nonvolatile = fr->nonvolatile,
+        .unmergeable = fr->unmergeable,
     };
 }
 
@@ -250,7 +252,8 @@ static bool flatrange_equal(FlatRange *a, FlatRange *b)
         && a->offset_in_region == b->offset_in_region
         && a->romd_mode == b->romd_mode
         && a->readonly == b->readonly
-        && a->nonvolatile == b->nonvolatile;
+        && a->nonvolatile == b->nonvolatile
+        && a->unmergeable == b->unmergeable;
 }
 
 static FlatView *flatview_new(MemoryRegion *mr_root)
@@ -323,7 +326,8 @@ static bool can_merge(FlatRange *r1, FlatRange *r2)
         && r1->dirty_log_mask == r2->dirty_log_mask
         && r1->romd_mode == r2->romd_mode
         && r1->readonly == r2->readonly
-        && r1->nonvolatile == r2->nonvolatile;
+        && r1->nonvolatile == r2->nonvolatile
+        && !r1->unmergeable && !r2->unmergeable;
 }
 
 /* Attempt to simplify a view by merging adjacent ranges */
@@ -599,7 +603,8 @@ static void render_memory_region(FlatView *view,
                                  Int128 base,
                                  AddrRange clip,
                                  bool readonly,
-                                 bool nonvolatile)
+                                 bool nonvolatile,
+                                 bool unmergeable)
 {
     MemoryRegion *subregion;
     unsigned i;
@@ -616,6 +621,7 @@ static void render_memory_region(FlatView *view,
     int128_addto(&base, int128_make64(mr->addr));
     readonly |= mr->readonly;
     nonvolatile |= mr->nonvolatile;
+    unmergeable |= mr->unmergeable;
 
     tmp = addrrange_make(base, mr->size);
 
@@ -629,14 +635,14 @@ static void render_memory_region(FlatView *view,
         int128_subfrom(&base, int128_make64(mr->alias->addr));
         int128_subfrom(&base, int128_make64(mr->alias_offset));
         render_memory_region(view, mr->alias, base, clip,
-                             readonly, nonvolatile);
+                             readonly, nonvolatile, unmergeable);
         return;
     }
 
     /* Render subregions in priority order. */
     QTAILQ_FOREACH(subregion, &mr->subregions, subregions_link) {
         render_memory_region(view, subregion, base, clip,
-                             readonly, nonvolatile);
+                             readonly, nonvolatile, unmergeable);
     }
 
     if (!mr->terminates) {
@@ -652,6 +658,7 @@ static void render_memory_region(FlatView *view,
     fr.romd_mode = mr->romd_mode;
     fr.readonly = readonly;
     fr.nonvolatile = nonvolatile;
+    fr.unmergeable = unmergeable;
 
     /* Render the region itself into any gaps left by the current view. */
     for (i = 0; i < view->nr && int128_nz(remain); ++i) {
@@ -753,7 +760,7 @@ static FlatView *generate_memory_topology(MemoryRegion *mr)
     if (mr) {
         render_memory_region(view, mr, int128_zero(),
                              addrrange_make(int128_zero(), int128_2_64()),
-                             false, false);
+                             false, false, false);
     }
     flatview_simplify(view);
 
@@ -2755,6 +2762,18 @@ void memory_region_set_alias_offset(MemoryRegion *mr, hwaddr offset)
     memory_region_transaction_commit();
 }
 
+void memory_region_set_unmergeable(MemoryRegion *mr, bool unmergeable)
+{
+    if (unmergeable == mr->unmergeable) {
+        return;
+    }
+
+    memory_region_transaction_begin();
+    mr->unmergeable = unmergeable;
+    memory_region_update_pending |= mr->enabled;
+    memory_region_transaction_commit();
+}
+
 uint64_t memory_region_get_alignment(const MemoryRegion *mr)
 {
     return mr->align;
