diff --git a/hw/microblaze/petalogix_s3adsp1800_mmu.c b/hw/microblaze/petalogix_s3adsp1800_mmu.c
index 0506497ad0a..fbf52ba8f2f 100644
--- a/hw/microblaze/petalogix_s3adsp1800_mmu.c
+++ b/hw/microblaze/petalogix_s3adsp1800_mmu.c
@@ -121,6 +121,7 @@ petalogix_s3adsp1800_init(MachineState *machine)
     sysbus_connect_irq(SYS_BUS_DEVICE(dev), 0, irq[TIMER_IRQ]);
 
     dev = qdev_new("xlnx.xps-ethernetlite");
+    qdev_prop_set_bit(dev, "little-endian", !TARGET_BIG_ENDIAN);
     qemu_configure_nic_device(dev, true, NULL);
     qdev_prop_set_uint32(dev, "tx-ping-pong", 0);
     qdev_prop_set_uint32(dev, "rx-ping-pong", 0);
diff --git a/hw/net/xilinx_ethlite.c b/hw/net/xilinx_ethlite.c
index 14bf2b2e17a..103e53831a7 100644
--- a/hw/net/xilinx_ethlite.c
+++ b/hw/net/xilinx_ethlite.c
@@ -90,6 +90,7 @@ struct XlnxXpsEthLite
     NICState *nic;
     NICConf conf;
 
+    bool little_endian_model;
     uint32_t c_tx_pingpong;
     uint32_t c_rx_pingpong;
     unsigned int port_index; /* dual port RAM index */
@@ -183,10 +184,10 @@ static void port_tx_write(void *opaque, hwaddr addr, uint64_t value,
     }
 }
 
-static const MemoryRegionOps eth_porttx_ops = {
+static const MemoryRegionOps eth_porttx_ops[2] = {
+    [0 ... 1] = {
         .read = port_tx_read,
         .write = port_tx_write,
-        .endianness = DEVICE_NATIVE_ENDIAN,
         .impl = {
             .min_access_size = 4,
             .max_access_size = 4,
@@ -195,6 +196,9 @@ static const MemoryRegionOps eth_porttx_ops = {
             .min_access_size = 4,
             .max_access_size = 4,
         },
+    },
+    [0].endianness = DEVICE_BIG_ENDIAN,
+    [1].endianness = DEVICE_LITTLE_ENDIAN,
 };
 
 static uint64_t port_rx_read(void *opaque, hwaddr addr, unsigned int size)
@@ -232,10 +236,10 @@ static void port_rx_write(void *opaque, hwaddr addr, uint64_t value,
     }
 }
 
-static const MemoryRegionOps eth_portrx_ops = {
+static const MemoryRegionOps eth_portrx_ops[2] = {
+    [0 ... 1] = {
         .read = port_rx_read,
         .write = port_rx_write,
-        .endianness = DEVICE_NATIVE_ENDIAN,
         .impl = {
             .min_access_size = 4,
             .max_access_size = 4,
@@ -244,6 +248,9 @@ static const MemoryRegionOps eth_portrx_ops = {
             .min_access_size = 4,
             .max_access_size = 4,
         },
+    },
+    [0].endianness = DEVICE_BIG_ENDIAN,
+    [1].endianness = DEVICE_LITTLE_ENDIAN,
 };
 
 static bool eth_can_rx(NetClientState *nc)
@@ -328,7 +335,7 @@ static void xilinx_ethlite_realize(DeviceState *dev, Error **errp)
                                BUFSZ_MAX, &error_abort);
         memory_region_add_subregion(&s->container, 0x0800 * i, &s->port[i].txbuf);
         memory_region_init_io(&s->port[i].txio, OBJECT(dev),
-                              &eth_porttx_ops, s,
+                              &eth_porttx_ops[s->little_endian_model], s,
                               i ? "ethlite.tx[1]io" : "ethlite.tx[0]io",
                               4 * TX_MAX);
         memory_region_add_subregion(&s->container, i ? A_TX_BASE1 : A_TX_BASE0,
@@ -340,7 +347,7 @@ static void xilinx_ethlite_realize(DeviceState *dev, Error **errp)
         memory_region_add_subregion(&s->container, 0x1000 + 0x0800 * i,
                                     &s->port[i].rxbuf);
         memory_region_init_io(&s->port[i].rxio, OBJECT(dev),
-                              &eth_portrx_ops, s,
+                              &eth_portrx_ops[s->little_endian_model], s,
                               i ? "ethlite.rx[1]io" : "ethlite.rx[0]io",
                               4 * RX_MAX);
         memory_region_add_subregion(&s->container, i ? A_RX_BASE1 : A_RX_BASE0,
@@ -363,6 +370,7 @@ static void xilinx_ethlite_init(Object *obj)
 }
 
 static const Property xilinx_ethlite_properties[] = {
+    DEFINE_PROP_BOOL("little-endian", XlnxXpsEthLite, little_endian_model, true),
     DEFINE_PROP_UINT32("tx-ping-pong", XlnxXpsEthLite, c_tx_pingpong, 1),
     DEFINE_PROP_UINT32("rx-ping-pong", XlnxXpsEthLite, c_rx_pingpong, 1),
     DEFINE_NIC_PROPERTIES(XlnxXpsEthLite, conf),
