diff --git a/include/hw/virtio/virtio-scsi.h b/include/hw/virtio/virtio-scsi.h
index 7b7e3ced7a..086201efa2 100644
--- a/include/hw/virtio/virtio-scsi.h
+++ b/include/hw/virtio/virtio-scsi.h
@@ -22,6 +22,7 @@
 #include "hw/virtio/virtio.h"
 #include "hw/scsi/scsi.h"
 #include "chardev/char-fe.h"
+#include "qapi/qapi-types-virtio.h"
 #include "system/iothread.h"
 
 #define TYPE_VIRTIO_SCSI_COMMON "virtio-scsi-common"
@@ -60,6 +61,7 @@ struct VirtIOSCSIConf {
     CharBackend chardev;
     uint32_t boot_tpgt;
     IOThread *iothread;
+    IOThreadVirtQueueMappingList *iothread_vq_mapping_list;
 };
 
 struct VirtIOSCSI;
@@ -97,7 +99,7 @@ struct VirtIOSCSI {
     QTAILQ_HEAD(, VirtIOSCSIReq) tmf_bh_list;
 
     /* Fields for dataplane below */
-    AioContext *ctx; /* one iothread per virtio-scsi-pci for now */
+    AioContext **vq_aio_context; /* per-virtqueue AioContext pointer */
 
     bool dataplane_started;
     bool dataplane_starting;
@@ -115,6 +117,7 @@ void virtio_scsi_common_realize(DeviceState *dev,
 void virtio_scsi_common_unrealize(DeviceState *dev);
 
 void virtio_scsi_dataplane_setup(VirtIOSCSI *s, Error **errp);
+void virtio_scsi_dataplane_cleanup(VirtIOSCSI *s);
 int virtio_scsi_dataplane_start(VirtIODevice *s);
 void virtio_scsi_dataplane_stop(VirtIODevice *s);
 
diff --git a/hw/scsi/virtio-scsi-dataplane.c b/hw/scsi/virtio-scsi-dataplane.c
index f49ab98ecc..6bb368c8a5 100644
--- a/hw/scsi/virtio-scsi-dataplane.c
+++ b/hw/scsi/virtio-scsi-dataplane.c
@@ -18,6 +18,7 @@
 #include "system/block-backend.h"
 #include "hw/scsi/scsi.h"
 #include "scsi/constants.h"
+#include "hw/virtio/iothread-vq-mapping.h"
 #include "hw/virtio/virtio-bus.h"
 
 /* Context: BQL held */
@@ -27,8 +28,16 @@ void virtio_scsi_dataplane_setup(VirtIOSCSI *s, Error **errp)
     VirtIODevice *vdev = VIRTIO_DEVICE(s);
     BusState *qbus = qdev_get_parent_bus(DEVICE(vdev));
     VirtioBusClass *k = VIRTIO_BUS_GET_CLASS(qbus);
+    uint16_t num_vqs = vs->conf.num_queues + VIRTIO_SCSI_VQ_NUM_FIXED;
 
-    if (vs->conf.iothread) {
+    if (vs->conf.iothread && vs->conf.iothread_vq_mapping_list) {
+        error_setg(errp,
+                   "iothread and iothread-vq-mapping properties cannot be set "
+                   "at the same time");
+        return;
+    }
+
+    if (vs->conf.iothread || vs->conf.iothread_vq_mapping_list) {
         if (!k->set_guest_notifiers || !k->ioeventfd_assign) {
             error_setg(errp,
                        "device is incompatible with iothread "
@@ -39,13 +48,48 @@ void virtio_scsi_dataplane_setup(VirtIOSCSI *s, Error **errp)
             error_setg(errp, "ioeventfd is required for iothread");
             return;
         }
-        s->ctx = iothread_get_aio_context(vs->conf.iothread);
-    } else {
-        if (!virtio_device_ioeventfd_enabled(vdev)) {
+    }
+
+    s->vq_aio_context = g_new(AioContext *, num_vqs);
+
+    if (vs->conf.iothread_vq_mapping_list) {
+        if (!iothread_vq_mapping_apply(vs->conf.iothread_vq_mapping_list,
+                                       s->vq_aio_context, num_vqs, errp)) {
+            g_free(s->vq_aio_context);
+            s->vq_aio_context = NULL;
             return;
         }
-        s->ctx = qemu_get_aio_context();
+    } else if (vs->conf.iothread) {
+        AioContext *ctx = iothread_get_aio_context(vs->conf.iothread);
+        for (uint16_t i = 0; i < num_vqs; i++) {
+            s->vq_aio_context[i] = ctx;
+        }
+
+        /* Released in virtio_scsi_dataplane_cleanup() */
+        object_ref(OBJECT(vs->conf.iothread));
+    } else {
+        AioContext *ctx = qemu_get_aio_context();
+        for (unsigned i = 0; i < num_vqs; i++) {
+            s->vq_aio_context[i] = ctx;
+        }
+    }
+}
+
+/* Context: BQL held */
+void virtio_scsi_dataplane_cleanup(VirtIOSCSI *s)
+{
+    VirtIOSCSICommon *vs = VIRTIO_SCSI_COMMON(s);
+
+    if (vs->conf.iothread_vq_mapping_list) {
+        iothread_vq_mapping_cleanup(vs->conf.iothread_vq_mapping_list);
     }
+
+    if (vs->conf.iothread) {
+        object_unref(OBJECT(vs->conf.iothread));
+    }
+
+    g_free(s->vq_aio_context);
+    s->vq_aio_context = NULL;
 }
 
 static int virtio_scsi_set_host_notifier(VirtIOSCSI *s, VirtQueue *vq, int n)
@@ -66,31 +110,20 @@ static int virtio_scsi_set_host_notifier(VirtIOSCSI *s, VirtQueue *vq, int n)
 }
 
 /* Context: BH in IOThread */
-static void virtio_scsi_dataplane_stop_bh(void *opaque)
+static void virtio_scsi_dataplane_stop_vq_bh(void *opaque)
 {
-    VirtIOSCSI *s = opaque;
-    VirtIOSCSICommon *vs = VIRTIO_SCSI_COMMON(s);
+    AioContext *ctx = qemu_get_current_aio_context();
+    VirtQueue *vq = opaque;
     EventNotifier *host_notifier;
-    int i;
 
-    virtio_queue_aio_detach_host_notifier(vs->ctrl_vq, s->ctx);
-    host_notifier = virtio_queue_get_host_notifier(vs->ctrl_vq);
+    virtio_queue_aio_detach_host_notifier(vq, ctx);
+    host_notifier = virtio_queue_get_host_notifier(vq);
 
     /*
      * Test and clear notifier after disabling event, in case poll callback
      * didn't have time to run.
      */
     virtio_queue_host_notifier_read(host_notifier);
-
-    virtio_queue_aio_detach_host_notifier(vs->event_vq, s->ctx);
-    host_notifier = virtio_queue_get_host_notifier(vs->event_vq);
-    virtio_queue_host_notifier_read(host_notifier);
-
-    for (i = 0; i < vs->conf.num_queues; i++) {
-        virtio_queue_aio_detach_host_notifier(vs->cmd_vqs[i], s->ctx);
-        host_notifier = virtio_queue_get_host_notifier(vs->cmd_vqs[i]);
-        virtio_queue_host_notifier_read(host_notifier);
-    }
 }
 
 /* Context: BQL held */
@@ -154,11 +187,14 @@ int virtio_scsi_dataplane_start(VirtIODevice *vdev)
     smp_wmb(); /* paired with aio_notify_accept() */
 
     if (s->bus.drain_count == 0) {
-        virtio_queue_aio_attach_host_notifier(vs->ctrl_vq, s->ctx);
-        virtio_queue_aio_attach_host_notifier_no_poll(vs->event_vq, s->ctx);
+        virtio_queue_aio_attach_host_notifier(vs->ctrl_vq,
+                                              s->vq_aio_context[0]);
+        virtio_queue_aio_attach_host_notifier_no_poll(vs->event_vq,
+                                                      s->vq_aio_context[1]);
 
         for (i = 0; i < vs->conf.num_queues; i++) {
-            virtio_queue_aio_attach_host_notifier(vs->cmd_vqs[i], s->ctx);
+            AioContext *ctx = s->vq_aio_context[VIRTIO_SCSI_VQ_NUM_FIXED + i];
+            virtio_queue_aio_attach_host_notifier(vs->cmd_vqs[i], ctx);
         }
     }
     return 0;
@@ -207,7 +243,11 @@ void virtio_scsi_dataplane_stop(VirtIODevice *vdev)
     s->dataplane_stopping = true;
 
     if (s->bus.drain_count == 0) {
-        aio_wait_bh_oneshot(s->ctx, virtio_scsi_dataplane_stop_bh, s);
+        for (i = 0; i < vs->conf.num_queues + VIRTIO_SCSI_VQ_NUM_FIXED; i++) {
+            VirtQueue *vq = virtio_get_queue(&vs->parent_obj, i);
+            AioContext *ctx = s->vq_aio_context[i];
+            aio_wait_bh_oneshot(ctx, virtio_scsi_dataplane_stop_vq_bh, vq);
+        }
     }
 
     blk_drain_all(); /* ensure there are no in-flight requests */
diff --git a/hw/scsi/virtio-scsi.c b/hw/scsi/virtio-scsi.c
index 2045d27289..9f61eb97db 100644
--- a/hw/scsi/virtio-scsi.c
+++ b/hw/scsi/virtio-scsi.c
@@ -27,6 +27,7 @@
 #include "hw/qdev-properties.h"
 #include "hw/scsi/scsi.h"
 #include "scsi/constants.h"
+#include "hw/virtio/iothread-vq-mapping.h"
 #include "hw/virtio/virtio-bus.h"
 #include "hw/virtio/virtio-access.h"
 #include "trace.h"
@@ -318,13 +319,6 @@ static void virtio_scsi_cancel_notify(Notifier *notifier, void *data)
     g_free(n);
 }
 
-static inline void virtio_scsi_ctx_check(VirtIOSCSI *s, SCSIDevice *d)
-{
-    if (s->dataplane_started && d && blk_is_available(d->conf.blk)) {
-        assert(blk_get_aio_context(d->conf.blk) == s->ctx);
-    }
-}
-
 static void virtio_scsi_do_one_tmf_bh(VirtIOSCSIReq *req)
 {
     VirtIOSCSI *s = req->dev;
@@ -517,9 +511,11 @@ static void virtio_scsi_flush_defer_tmf_to_aio_context(VirtIOSCSI *s)
 
     assert(!s->dataplane_started);
 
-    if (s->ctx) {
+    for (uint32_t i = 0; i < s->parent_obj.conf.num_queues; i++) {
+        AioContext *ctx = s->vq_aio_context[VIRTIO_SCSI_VQ_NUM_FIXED + i];
+
         /* Our BH only runs after previously scheduled BHs */
-        aio_wait_bh_oneshot(s->ctx, dummy_bh, NULL);
+        aio_wait_bh_oneshot(ctx, dummy_bh, NULL);
     }
 }
 
@@ -575,7 +571,6 @@ static int virtio_scsi_do_tmf(VirtIOSCSI *s, VirtIOSCSIReq *req)
     AioContext *ctx;
     int ret = 0;
 
-    virtio_scsi_ctx_check(s, d);
     /* Here VIRTIO_SCSI_S_OK means "FUNCTION COMPLETE".  */
     req->resp.tmf.response = VIRTIO_SCSI_S_OK;
 
@@ -639,6 +634,8 @@ static int virtio_scsi_do_tmf(VirtIOSCSI *s, VirtIOSCSIReq *req)
 
     case VIRTIO_SCSI_T_TMF_ABORT_TASK_SET:
     case VIRTIO_SCSI_T_TMF_CLEAR_TASK_SET: {
+        g_autoptr(GHashTable) aio_contexts = g_hash_table_new(NULL, NULL);
+
         if (!d) {
             goto fail;
         }
@@ -648,8 +645,15 @@ static int virtio_scsi_do_tmf(VirtIOSCSI *s, VirtIOSCSIReq *req)
 
         qatomic_inc(&req->remaining);
 
-        ctx = s->ctx ?: qemu_get_aio_context();
-        virtio_scsi_defer_tmf_to_aio_context(req, ctx);
+        for (uint32_t i = 0; i < s->parent_obj.conf.num_queues; i++) {
+            ctx = s->vq_aio_context[VIRTIO_SCSI_VQ_NUM_FIXED + i];
+
+            if (!g_hash_table_add(aio_contexts, ctx)) {
+                continue; /* skip previously added AioContext */
+            }
+
+            virtio_scsi_defer_tmf_to_aio_context(req, ctx);
+        }
 
         virtio_scsi_tmf_dec_remaining(req);
         ret = -EINPROGRESS;
@@ -770,9 +774,12 @@ static void virtio_scsi_handle_ctrl_vq(VirtIOSCSI *s, VirtQueue *vq)
  */
 static bool virtio_scsi_defer_to_dataplane(VirtIOSCSI *s)
 {
-    if (!s->ctx || s->dataplane_started) {
+    if (s->dataplane_started) {
         return false;
     }
+    if (s->vq_aio_context[0] == qemu_get_aio_context()) {
+        return false; /* not using IOThreads */
+    }
 
     virtio_device_start_ioeventfd(&s->parent_obj.parent_obj);
     return !s->dataplane_fenced;
@@ -946,7 +953,6 @@ static int virtio_scsi_handle_cmd_req_prepare(VirtIOSCSI *s, VirtIOSCSIReq *req)
         virtio_scsi_complete_cmd_req(req);
         return -ENOENT;
     }
-    virtio_scsi_ctx_check(s, d);
     req->sreq = scsi_req_new(d, req->req.cmd.tag,
                              virtio_scsi_get_lun(req->req.cmd.lun),
                              req->req.cmd.cdb, vs->cdb_size, req);
@@ -1218,14 +1224,16 @@ static void virtio_scsi_hotplug(HotplugHandler *hotplug_dev, DeviceState *dev,
 {
     VirtIODevice *vdev = VIRTIO_DEVICE(hotplug_dev);
     VirtIOSCSI *s = VIRTIO_SCSI(vdev);
+    AioContext *ctx = s->vq_aio_context[VIRTIO_SCSI_VQ_NUM_FIXED];
     SCSIDevice *sd = SCSI_DEVICE(dev);
-    int ret;
 
-    if (s->ctx && !s->dataplane_fenced) {
-        ret = blk_set_aio_context(sd->conf.blk, s->ctx, errp);
-        if (ret < 0) {
-            return;
-        }
+    if (ctx != qemu_get_aio_context() && !s->dataplane_fenced) {
+        /*
+         * Try to make the BlockBackend's AioContext match ours. Ignore failure
+         * because I/O will still work although block jobs and other users
+         * might be slower when multiple AioContexts use a BlockBackend.
+         */
+        blk_set_aio_context(sd->conf.blk, ctx, errp);
     }
 
     if (virtio_vdev_has_feature(vdev, VIRTIO_SCSI_F_HOTPLUG)) {
@@ -1260,7 +1268,7 @@ static void virtio_scsi_hotunplug(HotplugHandler *hotplug_dev, DeviceState *dev,
 
     qdev_simple_device_unplug_cb(hotplug_dev, dev, errp);
 
-    if (s->ctx) {
+    if (s->vq_aio_context[VIRTIO_SCSI_VQ_NUM_FIXED] != qemu_get_aio_context()) {
         /* If other users keep the BlockBackend in the iothread, that's ok */
         blk_set_aio_context(sd->conf.blk, qemu_get_aio_context(), NULL);
     }
@@ -1294,7 +1302,7 @@ static void virtio_scsi_drained_begin(SCSIBus *bus)
 
     for (uint32_t i = 0; i < total_queues; i++) {
         VirtQueue *vq = virtio_get_queue(vdev, i);
-        virtio_queue_aio_detach_host_notifier(vq, s->ctx);
+        virtio_queue_aio_detach_host_notifier(vq, s->vq_aio_context[i]);
     }
 }
 
@@ -1320,10 +1328,12 @@ static void virtio_scsi_drained_end(SCSIBus *bus)
 
     for (uint32_t i = 0; i < total_queues; i++) {
         VirtQueue *vq = virtio_get_queue(vdev, i);
+        AioContext *ctx = s->vq_aio_context[i];
+
         if (vq == vs->event_vq) {
-            virtio_queue_aio_attach_host_notifier_no_poll(vq, s->ctx);
+            virtio_queue_aio_attach_host_notifier_no_poll(vq, ctx);
         } else {
-            virtio_queue_aio_attach_host_notifier(vq, s->ctx);
+            virtio_queue_aio_attach_host_notifier(vq, ctx);
         }
     }
 }
@@ -1430,12 +1440,13 @@ void virtio_scsi_common_unrealize(DeviceState *dev)
     virtio_cleanup(vdev);
 }
 
+/* main loop */
 static void virtio_scsi_device_unrealize(DeviceState *dev)
 {
     VirtIOSCSI *s = VIRTIO_SCSI(dev);
 
     virtio_scsi_reset_tmf_bh(s);
-
+    virtio_scsi_dataplane_cleanup(s);
     qbus_set_hotplug_handler(BUS(&s->bus), NULL);
     virtio_scsi_common_unrealize(dev);
     qemu_mutex_destroy(&s->tmf_bh_lock);
@@ -1460,6 +1471,8 @@ static const Property virtio_scsi_properties[] = {
                                                 VIRTIO_SCSI_F_CHANGE, true),
     DEFINE_PROP_LINK("iothread", VirtIOSCSI, parent_obj.conf.iothread,
                      TYPE_IOTHREAD, IOThread *),
+    DEFINE_PROP_IOTHREAD_VQ_MAPPING_LIST("iothread-vq-mapping", VirtIOSCSI,
+            parent_obj.conf.iothread_vq_mapping_list),
 };
 
 static const VMStateDescription vmstate_virtio_scsi = {
